Introducing Enterprise QC and Calibration Management in LabCollector LIMS – LSM v4.2

We are pleased to announce LSM v4.2, introducing a new Enterprise Quality Control and Calibration workbench for LabCollector LIMS. This release connects QC plans, calibration runs, laboratory instruments, analytical batches and customer results within a single controlled workflow — replacing disconnected spreadsheets and manual checks with a traceable, integrated quality process.

From QC Planning to Customer Results

Laboratories can now create version-controlled QC plans defining:

Standards, blanks, controls and replicates
Required instruments and reference materials
Run sequences and recurring checkpoints
Acceptance criteria and calculation rules
Validity periods and usage limits
Review, approval and activation requirements

Approved plans remain available while future revisions are drafted. When a replacement is approved, the previous version is retired without compromising historical runs.

QC Plans module in Lab Service Manager — version-controlled plans with draft and approved statuses — QC Plans — version-controlled plans with draft and approved statuses, side by side.

Controlled QC and Calibration Runs

The new QC Run Workspace guides analysts through execution:

Generate fresh internal QC jobs and samples
Enter or import results using standard LSM workflows
Record materials, lots and certificate values
Review each reference as Pass or Fail
Reanalyse failed references without losing previous evidence
Exclude unsuitable references with authorization and justification
Calculate governed outputs
Submit runs for review, approval and activation

Every important action is recorded in the audit trail.

QC Run Workspace — ordered run sheet with calibration outputs and audit timeline — QC Run Workspace — the ordered run sheet, live calibration outputs and audit timeline in one view.

Calibration Outputs in Customer Calculations

Approved QC outputs can be used directly in customer-result formulas through controlled variables such as:

{QC:XRF_FE_FACTOR}

LSM resolves each variable from the QC run assigned to the relevant batch, assay and instrument. Supported calculations include:

Recovery
Correction factors
Mean and standard deviation
Slope and intercept
R²
Minimum and maximum
Sequence-specific correction factors

Raw numerical precision is retained for calculations, while normal parameter settings control displayed rounding.

Results management — raw signals and calibrated concentrations governed by the assigned QC run — Customer results — raw signals and calibrated concentrations governed by the assigned QC run.

Reference-Level Acceptance

Plans can require an explicit Pass or Fail decision for each calibration reference. They can also define the minimum number of accepted references needed to calculate a factor — only accepted references contribute to governed averages.

A failed reference must be resolved by either:

Creating a fresh, traceable reanalysis; or
Recording a justified exclusion by an authorized user

This provides flexibility without weakening traceability.

Batch-Level QC Governance

LSM v4.2 introduces strong links between analytical batches and QC runs. Before customer results can progress, LSM verifies:

Required QC coverage
Instrument compatibility
Run validity
Available capacity
Checkpoint status
Factor availability
Assignment consistency

A single assay can be governed by separate QC runs for different instruments. Associations remain attached to the customer executions as permanent evidence. When a run no longer has sufficient capacity, LSM blocks the affected work and guides users toward preparing another run or splitting the remaining samples into a new batch.

Reusable Calibration and Batch Correction

Two operating models are supported:

Reusable calibration — one approved run can serve multiple compatible batches until its validity or capacity is exhausted.
Batch correction — the QC run and its factors are permanently associated with one analytical batch.

Correction factors can follow strategies such as:

Last accepted reference
Mean of accepted references to date
Final accepted run mean

This supports workflows where a reference measured after a defined number of customer samples becomes effective for the following sequence.

Quality Review and Impact Management

Authorized reviewers can inspect:

Run configuration and execution
Source observations
Reference decisions
Material and certificate evidence
Calculated outputs
Acceptance rules
Checkpoints
Audit history

QC Runs list — runs with IN_PROGRESS, DRAFT, ACTIVE and SUPERSEDED statuses — QC Runs — the full list with IN_PROGRESS, DRAFT, ACTIVE and SUPERSEDED statuses, including next checkpoints and remaining usage.

If an active QC run later fails or becomes unsuitable, LSM can identify potentially affected customer results and support documented impact assessment.

Built for Controlled Laboratory Environments

The new workbench includes:

Granular permissions
Separation of duties
Mandatory reasons for controlled actions
Immutable source-result snapshots
Optimistic locking and transactional updates
Audited QA overrides
Multilingual interfaces
A built-in HTML user manual
Demonstration data for evaluation and training

Available in LSM v4.2

Enterprise QC and Calibration Management is available as an optional feature in LSM v4.2 for LabCollector LIMS. It brings calibration evidence, analytical execution and customer reporting together — helping laboratories replace disconnected spreadsheets and manual checks with a traceable, integrated quality workflow.

Ready to see it in action? Visit LabCollector to learn more about LSM v4.2 and how the new QC & Calibration workbench can strengthen your laboratory's quality process.

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